6YJ3
Metala-Carborane di-propyl-sulfonamide
Summary for 6YJ3
Entry DOI | 10.2210/pdb6yj3/pdb |
Descriptor | Carbonic anhydrase 2, ZINC ION, Metala-Carborane di-propyl-sulfonamide, ... (4 entities in total) |
Functional Keywords | carbonic anhydrase ix, ca inhibitor, lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 30423.52 |
Authors | Brynda, J.,Rezacova, P.,Pospisilova, K.,Kugler, M. (deposition date: 2020-04-02, release date: 2020-09-09, Last modification date: 2024-01-24) |
Primary citation | Gruner, B.,Kugler, M.,El Anwar, S.,Holub, J.,Nekvinda, J.,Bavol, D.,Ruzickova, Z.,Pospisilova, K.,Fabry, M.,Kral, V.,Brynda, J.,Rezacova, P. Cobalt Bis(dicarbollide) Alkylsulfonamides: Potent and Highly Selective Inhibitors of Tumor Specific Carbonic Anhydrase IX. Chempluschem, 86:352-363, 2021 Cited by PubMed: 32955786DOI: 10.1002/cplu.202000574 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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