6Y9B
Cryo-EM structure of trimeric human STEAP1 bound to three Fab120.545 fragments
Summary for 6Y9B
| Entry DOI | 10.2210/pdb6y9b/pdb |
| EMDB information | 10735 |
| Descriptor | Metalloreductase STEAP1, Fab120.545 light chain, Fab120.545 heavy chain, ... (5 entities in total) |
| Functional Keywords | integral membrane protein heme-binding protein oxidoreductase antibody-antigen complex, membrane protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 9 |
| Total formula weight | 287657.92 |
| Authors | Oosterheert, W.,Gros, P. (deposition date: 2020-03-06, release date: 2020-05-20, Last modification date: 2020-07-22) |
| Primary citation | Oosterheert, W.,Gros, P. Cryo-electron microscopy structure and potential enzymatic function of human six-transmembrane epithelial antigen of the prostate 1 (STEAP1). J.Biol.Chem., 295:9502-9512, 2020 Cited by PubMed: 32409586DOI: 10.1074/jbc.RA120.013690 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.97 Å) |
Structure validation
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