6Y1Z
Mouse serotonin 5HT3 receptor in complex with palonosetron
Summary for 6Y1Z
Entry DOI | 10.2210/pdb6y1z/pdb |
EMDB information | 10673 |
Descriptor | 5-hydroxytryptamine receptor 3A, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | receptor, pentameric ligand-gated ion channel, antiemetic, transport protein |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 5 |
Total formula weight | 327858.32 |
Authors | Zarkadas, E.,Perot, J.,Nury, H. (deposition date: 2020-02-14, release date: 2020-03-04, Last modification date: 2022-09-14) |
Primary citation | Zarkadas, E.,Zhang, H.,Cai, W.,Effantin, G.,Perot, J.,Neyton, J.,Chipot, C.,Schoehn, G.,Dehez, F.,Nury, H. The Binding of Palonosetron and Other Antiemetic Drugs to the Serotonin 5-HT3 Receptor. Structure, 28:1131-1140.e4, 2020 Cited by PubMed: 32726573DOI: 10.1016/j.str.2020.07.004 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.82 Å) |
Structure validation
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