6XP6
3C11-DQ2-glia-a2 complex
Summary for 6XP6
Entry DOI | 10.2210/pdb6xp6/pdb |
Descriptor | MHC class II HLA-DQ-alpha chain, ISOPROPYL ALCOHOL, CHLORIDE ION, ... (12 entities in total) |
Functional Keywords | complex antibody human leucocyte antigen, peptide binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 192975.41 |
Authors | Petersen, J.,Rossjohn, J. (deposition date: 2020-07-08, release date: 2021-07-28, Last modification date: 2023-10-18) |
Primary citation | Frick, R.,Hoydahl, L.S.,Petersen, J.,du Pre, M.F.,Kumari, S.,Berntsen, G.,Dewan, A.E.,Jeliazkov, J.R.,Gunnarsen, K.S.,Frigstad, T.,Vik, E.S.,Llerena, C.,Lundin, K.E.A.,Yaqub, S.,Jahnsen, J.,Gray, J.J.,Rossjohn, J.,Sollid, L.M.,Sandlie, I.,Loset, G.A. A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation. Sci Immunol, 6:-, 2021 Cited by PubMed: 34417258DOI: 10.1126/sciimmunol.abg4925 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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