6WB8
Cryo-EM structure of PKD2 C331S disease variant
Summary for 6WB8
Entry DOI | 10.2210/pdb6wb8/pdb |
EMDB information | 21586 |
Descriptor | Polycystin-2, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total) |
Functional Keywords | pkd2, transport protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 348722.62 |
Authors | Cao, E.,Wang, J.,Decaen, P.G. (deposition date: 2020-03-26, release date: 2020-04-22, Last modification date: 2020-07-29) |
Primary citation | Vien, T.N.,Wang, J.,Ng, L.C.T.,Cao, E.,DeCaen, P.G. Molecular dysregulation of ciliary polycystin-2 channels caused by variants in the TOP domain. Proc.Natl.Acad.Sci.USA, 117:10329-10338, 2020 Cited by PubMed: 32332171DOI: 10.1073/pnas.1920777117 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.24 Å) |
Structure validation
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