6WAD
Crystal Structure of Human Protein arginine N-methyltransferase 6 (PRMT6) in complex with MT2739 inhibitor
Summary for 6WAD
Entry DOI | 10.2210/pdb6wad/pdb |
Descriptor | Protein arginine N-methyltransferase 6, S-ADENOSYL-L-HOMOCYSTEINE, 5-bromo-N-(diphenylmethyl)-N-methylthiophene-2-carboxamide, ... (4 entities in total) |
Functional Keywords | prmt6 and mt2739 inhibitor, structural genomics, structural genomics consortium, sgc, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 42845.28 |
Authors | Halabelian, L.,Zeng, H.,Dong, A.,Schapira, M.,De Freitas, R.F.,Hutchinson, A.,Seitova, A.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Brown, P.J.,Structural Genomics Consortium (SGC) (deposition date: 2020-03-25, release date: 2020-09-02, Last modification date: 2023-10-18) |
Primary citation | Halabelian, L.,Zeng, H.,Dong, A.,Schapira, M.,De Freitas, R.F.,Hutchinson, A.,Seitova, A.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Brown, P.J.,Structural Genomics Consortium (SGC) Crystal Structure of Human Protein arginine N-methyltransferase 6 (PRMT6) in complex with MT2739 inhibitor to be published, |
Experimental method |
Structure validation
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