6VR3
Aminoglycoside N-2'-Acetyltransferase-Ia [AAC(2')-Ia] in complex with acetylated-netilmicin and CoA
Summary for 6VR3
Entry DOI | 10.2210/pdb6vr3/pdb |
Related | 6VOU 6VR2 |
Descriptor | Aminoglycoside 2'-N-acetyltransferase, N-[(2S,3R)-2-{[(1R,2S,3S,4R,6S)-6-amino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-lyxopyranosyl]oxy}-4-(ethylamino) -2-hydroxycyclohexyl]oxy}-6-(aminomethyl)-3,4-dihydro-2H-pyran-3-yl]acetamide, COENZYME A, ... (4 entities in total) |
Functional Keywords | acetyltransferase, gnat superfamily, transferase |
Biological source | Providencia stuartii |
Total number of polymer chains | 2 |
Total formula weight | 43063.98 |
Authors | Bassenden, A.V.,Berghuis, A.M. (deposition date: 2020-02-06, release date: 2021-06-02, Last modification date: 2023-10-11) |
Primary citation | Bassenden, A.V.,Dumalo, L.,Park, J.,Blanchet, J.,Maiti, K.,Arya, D.P.,Berghuis, A.M. Structural and phylogenetic analyses of resistance to next-generation aminoglycosides conferred by AAC(2') enzymes. Sci Rep, 11:11614-11614, 2021 Cited by PubMed: 34078922DOI: 10.1038/s41598-021-89446-3 PDB entries with the same primary citation |
Experimental method |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)