6VC2
LRH-1 bound to SS-RJW100 and a fragment of the Tif2 Coactivator
Summary for 6VC2
Entry DOI | 10.2210/pdb6vc2/pdb |
Descriptor | Nuclear receptor subfamily 5 group A member 2, Nuclear receptor coactivator 2, (1S,3aS,6aS)-5-hexyl-4-phenyl-3a-(1-phenylethenyl)-1,2,3,3a,6,6a-hexahydropentalen-1-ol, ... (4 entities in total) |
Functional Keywords | nuclear hormone receptor, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 30527.30 |
Authors | Mays, S.G.,Ortlund, E.A. (deposition date: 2019-12-20, release date: 2020-12-23, Last modification date: 2023-10-11) |
Primary citation | Mays, S.G.,Stec, J.,Liu, X.,D'Agostino, E.H.,Whitby, R.J.,Ortlund, E.A. Enantiomer-specific activities of an LRH-1 and SF-1 dual agonist. Sci Rep, 10:22279-22279, 2020 Cited by PubMed: 33335203DOI: 10.1038/s41598-020-79251-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.697 Å) |
Structure validation
Download full validation report