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6VC2

LRH-1 bound to SS-RJW100 and a fragment of the Tif2 Coactivator

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Nuclear receptor subfamily 5 group A member 2polymer24528330.71UniProt (O00482)
Pfam (PF00104)
Homo sapiens (Human)Alpha-1-fetoprotein transcription factor,B1-binding factor,hB1F,CYP7A promoter-binding factor,Hepatocytic transcription factor,Liver receptor homolog 1,LRH-1
2B
(C)
Nuclear receptor coactivator 2polymer151810.01UniProt (Q15596)Homo sapiensNCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2
3C
(A)
(1S,3aS,6aS)-5-hexyl-4-phenyl-3a-(1-phenylethenyl)-1,2,3,3a,6,6a-hexahydropentalen-1-olnon-polymer386.61Chemie (QU7)
4D, E
(A, C)
waterwater18.0107Chemie (HOH)
Sequence modifications
A: 299 - 541 (UniProt: O00482)
PDBExternal DatabaseDetails
Ser 297-expression tag
Asn 298-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight30140.7
Non-Polymers*Number of molecules1
Total formula weight386.6
All*Total formula weight30527.3
*Water molecules are not included.

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PDB entries from 2025-10-08

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