6VA8
Crystal structure of glucose-6-phosphate dehydrogenase F381L mutant in complex with catalytic NADP+
Summary for 6VA8
Entry DOI | 10.2210/pdb6va8/pdb |
Descriptor | Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (2 entities in total) |
Functional Keywords | dehydrogenase, nadp+, rossmann-fold, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 60041.97 |
Authors | Horikoshi, N.,Mochly-Rosen, D.,Wakatsuki, S. (deposition date: 2019-12-17, release date: 2021-01-27, Last modification date: 2023-10-11) |
Primary citation | Horikoshi, N.,Hwang, S.,Gati, C.,Matsui, T.,Castillo-Orellana, C.,Raub, A.G.,Garcia, A.A.,Jabbarpour, F.,Batyuk, A.,Broweleit, J.,Xiang, X.,Chiang, A.,Broweleit, R.,Vohringer-Martinez, E.,Mochly-Rosen, D.,Wakatsuki, S. Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 33468660DOI: 10.1073/pnas.2022790118 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.95 Å) |
Structure validation
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