6VA8
Crystal structure of glucose-6-phosphate dehydrogenase F381L mutant in complex with catalytic NADP+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glucose-6-phosphate 1-dehydrogenase | polymer | 515 | 59298.6 | 1 | UniProt (P11413) Pfam (PF00479) Pfam (PF02781) | Homo sapiens (Human) | G6PD |
| 2 | B (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (71717786) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (165382010) |
Sequence modifications
A: 1 - 515 (UniProt: P11413)
| PDB | External Database | Details |
|---|---|---|
| Leu 381 | Phe 381 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 59298.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 743.4 | |
| All* | Total formula weight | 60042.0 |
