6URM

Crystal structure of vaccine-elicited receptor-binding site targeting antibody LPAF-a.01 in complex with Hemagglutinin H1 A/California/04/2009

Summary for 6URM

Entry DOI	10.2210/pdb6urm/pdb
Descriptor	Hemagglutinin, The heavy chain of antibody LPAF-a.01, The light chain of antibody LPAF-a.01, ... (9 entities in total)
Functional Keywords	influenza, antibody, receptor-binding site, immune system, immune system-viral protein complex, immune system/viral protein
Biological source	Influenza A virus More
Total number of polymer chains	6
Total formula weight	209012.82
Authors	Zhou, T.,Cheung, S.F.,Kwong, P.D. (deposition date: 2019-10-23, release date: 2020-09-16, Last modification date: 2023-10-11)
Primary citation	Cheung, C.S.,Fruehwirth, A.,Paparoditis, P.C.G.,Shen, C.H.,Foglierini, M.,Joyce, M.G.,Leung, K.,Piccoli, L.,Rawi, R.,Silacci-Fregni, C.,Tsybovsky, Y.,Verardi, R.,Wang, L.,Wang, S.,Yang, E.S.,Zhang, B.,Zhang, Y.,Chuang, G.Y.,Corti, D.,Mascola, J.R.,Shapiro, L.,Kwong, P.D.,Lanzavecchia, A.,Zhou, T. Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodies Reveal the Mechanism for Its Recurrent Elicitation. Cell Rep, 32:108088-108088, 2020 Cited by PubMed: 32877670 DOI: 10.1016/j.celrep.2020.108088 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.65 Å)

Structure validation