6U2J
EM structure of MPEG-1 (L425K, alpha conformation) soluble pre-pore complex
Summary for 6U2J
Entry DOI | 10.2210/pdb6u2j/pdb |
EMDB information | 20616 20617 20619 20620 20621 20622 20623 |
Descriptor | Macrophage-expressed gene 1 protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | mpeg-1/perforin-2, macpf, macrophage, pore forming proteins, immunity, immune system |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 16 |
Total formula weight | 1148348.11 |
Authors | Pang, S.S.,Bayly-Jones, C. (deposition date: 2019-08-20, release date: 2019-09-25, Last modification date: 2020-07-29) |
Primary citation | Pang, S.S.,Bayly-Jones, C.,Radjainia, M.,Spicer, B.A.,Law, R.H.P.,Hodel, A.W.,Parsons, E.S.,Ekkel, S.M.,Conroy, P.J.,Ramm, G.,Venugopal, H.,Bird, P.I.,Hoogenboom, B.W.,Voskoboinik, I.,Gambin, Y.,Sierecki, E.,Dunstone, M.A.,Whisstock, J.C. The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1. Nat Commun, 10:4288-4288, 2019 Cited by PubMed: 31537793DOI: 10.1038/s41467-019-12279-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.37 Å) |
Structure validation
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