6TYM
KEAP1 Kelch domain in complex with Compound 9
Summary for 6TYM
Entry DOI | 10.2210/pdb6tym/pdb |
Descriptor | Kelch-like ECH-associated protein 1, GLYCEROL, DIMETHYL SULFOXIDE, ... (5 entities in total) |
Functional Keywords | keap1 kelch domain, peptide binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 33203.22 |
Authors | Marcotte, D.J. (deposition date: 2019-08-09, release date: 2020-01-15, Last modification date: 2023-10-11) |
Primary citation | Ma, B.,Lucas, B.,Capacci, A.,Lin, E.Y.,Jones, J.H.,Dechantsreiter, M.,Enyedy, I.,Marcotte, D.,Xiao, G.,Li, B.,Richter, K. Design, synthesis and identification of novel, orally bioavailable non-covalent Nrf2 activators. Bioorg.Med.Chem.Lett., 30:126852-126852, 2020 Cited by PubMed: 31898999DOI: 10.1016/j.bmcl.2019.126852 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.422 Å) |
Structure validation
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