6TYM
KEAP1 Kelch domain in complex with Compound 9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Kelch-like ECH-associated protein 1 | polymer | 293 | 32067.8 | 1 | UniProt (Q14145) Pfam (PF01344) | Homo sapiens (Human) | Cytosolic inhibitor of Nrf2,INrf2,Kelch-like protein 19 |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | D, E (A) | (3S)-3-[2-(benzenecarbonyl)-5-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl]-3-(1-ethyl-4-methyl-1H-benzotriazol-5-yl)propanoic acid | non-polymer | 482.6 | 2 | Chemie (08A) | |||
| 5 | F (A) | water | water | 18.0 | 309 | Chemie (HOH) |
Sequence modifications
A: 321 - 609 (UniProt: Q14145)
| PDB | External Database | Details |
|---|---|---|
| Gly 317 | - | expression tag |
| Ser 318 | - | expression tag |
| His 319 | - | expression tag |
| Met 320 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32067.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1135.4 | |
| All* | Total formula weight | 33203.2 |
