Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008134 | molecular_function | transcription factor binding |
| A | 0016567 | biological_process | protein ubiquitination |
| A | 0031463 | cellular_component | Cul3-RING ubiquitin ligase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 701 |
| Chain | Residue |
| A | PHE335 |
| A | ARG336 |
| A | THR576 |
| A | PHE577 |
| A | 08A703 |
| A | HOH995 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 702 |
| Chain | Residue |
| A | 08A703 |
| A | 08A704 |
| A | ARG415 |
| A | THR541 |
| A | GLU542 |
| site_id | AC3 |
| Number of Residues | 20 |
| Details | binding site for residue 08A A 703 |
| Chain | Residue |
| A | TYR334 |
| A | ARG380 |
| A | ASN382 |
| A | ASN387 |
| A | ASN414 |
| A | ARG415 |
| A | MET499 |
| A | ILE500 |
| A | THR501 |
| A | THR543 |
| A | TYR572 |
| A | HIS575 |
| A | GOL701 |
| A | DMS702 |
| A | 08A704 |
| A | HOH801 |
| A | HOH867 |
| A | HOH895 |
| A | HOH905 |
| A | HOH948 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | binding site for residue 08A A 704 |
| Chain | Residue |
| A | TYR334 |
| A | GLY364 |
| A | ARG415 |
| A | ILE461 |
| A | PHE478 |
| A | ARG483 |
| A | SER508 |
| A | TYR525 |
| A | GLN530 |
| A | GLU542 |
| A | SER555 |
| A | TYR572 |
| A | PHE577 |
| A | SER602 |
| A | GLY603 |
| A | DMS702 |
| A | 08A703 |
| A | HOH849 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 45 |
| Details | Repeat: {"description":"Kelch 1"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 50 |
| Details | Repeat: {"description":"Kelch 2"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"Kelch 3"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"Kelch 4"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"Kelch 5"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Site: {"description":"Sensor for electrophilic agents","evidences":[{"source":"UniProtKB","id":"Q9Z2X8","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"S-cGMP-cysteine","evidences":[{"source":"UniProtKB","id":"Q9Z2X8","evidenceCode":"ECO:0000250"}]} |
