6TKL
Non-cleavable tsetse thrombin inhibitor in complex with human alpha-thrombin
Summary for 6TKL
Entry DOI | 10.2210/pdb6tkl/pdb |
Related | 6TKG 6TKH 6TKI 6TKJ |
Descriptor | Prothrombin, Tsetse thrombin inhibitor, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | anticoagulant tyrosine sulfation posttranslational modification complex, blood clotting |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 40189.82 |
Authors | Calisto, B.M.,Ripoll-Rozada, J.,de Sanctis, D.,Pereira, P.J.B. (deposition date: 2019-11-28, release date: 2020-11-04, Last modification date: 2024-01-24) |
Primary citation | Calisto, B.M.,Ripoll-Rozada, J.,Dowman, L.J.,Franck, C.,Agten, S.M.,Parker, B.L.,Veloso, R.C.,Vale, N.,Gomes, P.,de Sanctis, D.,Payne, R.J.,Pereira, P.J.B. Sulfotyrosine-Mediated Recognition of Human Thrombin by a Tsetse Fly Anticoagulant Mimics Physiological Substrates. Cell Chem Biol, 28:26-, 2021 Cited by PubMed: 33096052DOI: 10.1016/j.chembiol.2020.10.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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