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6TKJ

Tsetse thrombin inhibitor in complex with human alpha-thrombin - tetragonal form at 7keV

Summary for 6TKJ
Entry DOI10.2210/pdb6tkj/pdb
Related6TKG 6TKH 6TKI
DescriptorThrombin light chain, Thrombin heavy chain, Tsetse thrombin inhibitor, ... (5 entities in total)
Functional Keywordsanticoagulant tyrosine sulfation posttranslational modification complex, blood clotting
Biological sourceHomo sapiens (Human)
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Total number of polymer chains3
Total formula weight40060.71
Authors
Calisto, B.M.,Ripoll-Rozada, J.,de Sanctis, D.,Pereira, P.J.B. (deposition date: 2019-11-28, release date: 2020-11-04, Last modification date: 2024-01-24)
Primary citationCalisto, B.M.,Ripoll-Rozada, J.,Dowman, L.J.,Franck, C.,Agten, S.M.,Parker, B.L.,Veloso, R.C.,Vale, N.,Gomes, P.,de Sanctis, D.,Payne, R.J.,Pereira, P.J.B.
Sulfotyrosine-Mediated Recognition of Human Thrombin by a Tsetse Fly Anticoagulant Mimics Physiological Substrates.
Cell Chem Biol, 28:26-, 2021
Cited by
PubMed: 33096052
DOI: 10.1016/j.chembiol.2020.10.002
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.81 Å)
Structure validation

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