6T9N
CryoEM structure of human polycystin-2/PKD2 in UDM supplemented with PI(4,5)P2
Summary for 6T9N
Entry DOI | 10.2210/pdb6t9n/pdb |
EMDB information | 10418 |
Descriptor | Polycystin-2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... (6 entities in total) |
Functional Keywords | ion channel, transient receptor potential channel, polycystic kidney disease, structural genomics, structural genomics consortium, sgc, membrane protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 276891.48 |
Authors | Wang, Q.,Pike, A.C.W.,Grieben, M.,Baronina, A.,Nasrallah, C.,Shintre, C.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Carpenter, E.P.,Structural Genomics Consortium (SGC) (deposition date: 2019-10-28, release date: 2019-11-20, Last modification date: 2020-07-29) |
Primary citation | Wang, Q.,Corey, R.A.,Hedger, G.,Aryal, P.,Grieben, M.,Nasrallah, C.,Baronina, A.,Pike, A.C.W.,Shi, J.,Carpenter, E.P.,Sansom, M.S.P. Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2. Structure, 28:169-184.e5, 2020 Cited by PubMed: 31806353DOI: 10.1016/j.str.2019.11.005 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.96 Å) |
Structure validation
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