6RQJ
Structure of human complement C5 complexed with tick inhibitors OmCI, RaCI1 and CirpT1
Summary for 6RQJ
Entry DOI | 10.2210/pdb6rqj/pdb |
Related | 6rpt |
EMDB information | 4983 |
Descriptor | Complement C5, Complement inhibitor, Rhipicephalus appendiculatus RaCI1, ... (6 entities in total) |
Functional Keywords | complement, inhibitor, innate immunity, inflammation, c5, terminal pathway inhibitor, immunosuppressant |
Biological source | Rhipicephalus pulchellus More |
Total number of polymer chains | 5 |
Total formula weight | 225798.83 |
Authors | Reichhardt, M.P.,Johnson, S.,Lea, S.M. (deposition date: 2019-05-15, release date: 2020-01-08, Last modification date: 2020-07-29) |
Primary citation | Reichhardt, M.P.,Johnson, S.,Tang, T.,Morgan, T.,Tebeka, N.,Popitsch, N.,Deme, J.C.,Jore, M.M.,Lea, S.M. An inhibitor of complement C5 provides structural insights into activation. Proc.Natl.Acad.Sci.USA, 117:362-370, 2020 Cited by PubMed: 31871188DOI: 10.1073/pnas.1909973116 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
Download full validation report