6R8J

Crystal structure of di-phosphorylated human CLK1 in complex with 4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine

Summary for 6R8J

• Entry DOI: 10.2210/pdb6r8j/pdb
• Related: 2VAG
• Descriptor: Dual specificity protein kinase CLK1, 4-(1-methylindol-3-yl)pyrimidin-2-amine (3 entities in total)
• Functional Keywords: clk1, splicing, kinase, viral infection, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 39897.87

Authors

Livnah, O.,Domovich, Y. (deposition date: 2019-04-02, release date: 2020-05-13, Last modification date: 2024-05-15)

• Primary citation: Livnah, O.,Domovich, Y.; Non-phosphorylated human CLK1 in complex with an indole inhibitor to 1.65 Ang; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.75 Å)