6R4N
Crystal structure of S. cerevisia Niemann-Pick type C protein NPC2 with ergosterol bound
Summary for 6R4N
Entry DOI | 10.2210/pdb6r4n/pdb |
Related | 6R4M |
Descriptor | Phosphatidylglycerol/phosphatidylinositol transfer protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | vacuole, ergosterol, lipid transport |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Total number of polymer chains | 9 |
Total formula weight | 202037.03 |
Authors | Winkler, M.B.L.,Kidmose, R.T.,Pedersen, B.P. (deposition date: 2019-03-22, release date: 2019-09-25, Last modification date: 2020-07-29) |
Primary citation | Winkler, M.B.L.,Kidmose, R.T.,Szomek, M.,Thaysen, K.,Rawson, S.,Muench, S.P.,Wustner, D.,Pedersen, B.P. Structural Insight into Eukaryotic Sterol Transport through Niemann-Pick Type C Proteins. Cell, 179:485-497.e18, 2019 Cited by PubMed: 31543266DOI: 10.1016/j.cell.2019.08.038 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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