6R4N
Crystal structure of S. cerevisia Niemann-Pick type C protein NPC2 with ergosterol bound
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Phosphatidylglycerol/phosphatidylinositol transfer protein | polymer | 201 | 21813.6 | 9 | UniProt (Q12408) Pfam (PF02221) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PG/PI-TP,NPC2 homolog |
2 | J | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
3 | G, H, A, B, C... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) | |||
4 | A, I, C, E | ERGOSTEROL | non-polymer | 396.6 | 5 | Chemie (ERG) | |||
5 | F, G, H, I, A... | SULFATE ION | non-polymer | 96.1 | 16 | Chemie (SO4) |
Sequence modifications
A, B, C, D, E, F, G, H, I: 1 - 173 (UniProt: Q12408)
PDB | External Database | Details |
---|---|---|
Leu 174 | - | expression tag |
Val 175 | - | expression tag |
Pro 176 | - | expression tag |
Arg 177 | - | expression tag |
Gly 178 | - | expression tag |
Ser 179 | - | expression tag |
Gly 180 | - | expression tag |
Gly 181 | - | expression tag |
Gly 182 | - | expression tag |
Gly 183 | - | expression tag |
Ser 184 | - | expression tag |
Gly 185 | - | expression tag |
Gly 186 | - | expression tag |
Gly 187 | - | expression tag |
Gly 188 | - | expression tag |
Ser 189 | - | expression tag |
Gly 190 | - | expression tag |
Gly 191 | - | expression tag |
His 192 | - | expression tag |
His 193 | - | expression tag |
His 194 | - | expression tag |
His 195 | - | expression tag |
His 196 | - | expression tag |
His 197 | - | expression tag |
His 198 | - | expression tag |
His 199 | - | expression tag |
His 200 | - | expression tag |
His 201 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 9 |
Total formula weight | 196322.7 | |
Branched | Number of molecules | 1 |
Total formula weight | 424.4 | |
Non-Polymers* | Number of molecules | 29 |
Total formula weight | 5289.9 | |
All* | Total formula weight | 202037.0 |