6QJU

Crystal structure of human Bromodomain containing protein 3 (BRD3) in complex with 3-bromo-1H-indazol-5-amine

Summary for 6QJU

• Entry DOI: 10.2210/pdb6qju/pdb
• Descriptor: Bromodomain-containing protein 3, 1,2-ETHANEDIOL, THIOCYANATE ION, ... (7 entities in total)
• Functional Keywords: bromodomain, complex, inhibitor, ligand, halogen bonding, xb, heflib, halogen-enriched fragment library, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 29754.13

Authors

Braun, M.B.,Stehle, T.,Heidrich, J. (deposition date: 2019-01-25, release date: 2020-02-12, Last modification date: 2024-01-24)

• Primary citation: Braun, M.B.,Stehle, S.,Heidrich, J.,Boeckler, F.M.; Br-O-modomain (BRD3) halogen binding to a small molecule; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.202 Å)