6Q4Y
Structure of MPT-2, a GDP-Man-dependent mannosyltransferase from Leishmania mexicana, in complex with mannose
Summary for 6Q4Y
Entry DOI | 10.2210/pdb6q4y/pdb |
Descriptor | LmxM MPT-2, beta-D-mannopyranose, alpha-D-mannopyranose, ... (4 entities in total) |
Functional Keywords | transferase |
Biological source | Leishmania mexicana MHOM/GT/2001/U1103 |
Total number of polymer chains | 2 |
Total formula weight | 77087.27 |
Authors | Sobala, L.F.,Males, A.,Bastidas, L.M.,Ward, T.,Sernee, M.F.,Ralton, J.E.,Nero, T.L.,Cobbold, S.,Kloehn, J.,Viera-Lara, M.,Stanton, L.,Hanssen, E.,Parker, M.W.,Williams, S.J.,McConville, M.J.,Davies, G.J. (deposition date: 2018-12-06, release date: 2019-09-18, Last modification date: 2024-01-24) |
Primary citation | Sernee, M.F.,Ralton, J.E.,Nero, T.L.,Sobala, L.F.,Kloehn, J.,Vieira-Lara, M.A.,Cobbold, S.A.,Stanton, L.,Pires, D.E.V.,Hanssen, E.,Males, A.,Ward, T.,Bastidas, L.M.,van der Peet, P.L.,Parker, M.W.,Ascher, D.B.,Williams, S.J.,Davies, G.J.,McConville, M.J. A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites. Cell Host Microbe, 26:385-399.e9, 2019 Cited by PubMed: 31513773DOI: 10.1016/j.chom.2019.08.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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