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6Q21

MOLECULAR SWITCH FOR SIGNAL TRANSDUCTION: STRUCTURAL DIFFERENCES BETWEEN ACTIVE AND INACTIVE FORMS OF PROTOONCOGENIC RAS PROTEINS

Summary for 6Q21
Entry DOI10.2210/pdb6q21/pdb
DescriptorC-H-RAS P21 PROTEIN CATALYTIC DOMAIN, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... (4 entities in total)
Functional Keywordsoncogene protein
Biological sourceHomo sapiens (human)
Cellular locationCell membrane. Isoform 2: Nucleus: P01112
Total number of polymer chains4
Total formula weight80250.30
Authors
Kim, S.-H. (deposition date: 1992-07-27, release date: 1992-07-28, Last modification date: 2024-03-13)
Primary citationMilburn, M.V.,Tong, L.,deVos, A.M.,Brunger, A.,Yamaizumi, Z.,Nishimura, S.,Kim, S.H.
Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins.
Science, 247:939-945, 1990
Cited by
PubMed: 2406906
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

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