6PXQ
Crystal structure of human thrombin mutant D194A
Summary for 6PXQ
Entry DOI | 10.2210/pdb6pxq/pdb |
Related | 1PPB |
Descriptor | Thrombin light chain, Thrombin heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | hydrolase, trypsin-like proteases, ionic interaction |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 33748.62 |
Authors | Stojanovski, B.,Chen, Z.,Koester, S.K.,Pelc, L.A.,Di Cera, E. (deposition date: 2019-07-26, release date: 2019-12-18, Last modification date: 2023-10-11) |
Primary citation | Stojanovski, B.M.,Chen, Z.,Koester, S.K.,Pelc, L.A.,Di Cera, E. Role of the I16-D194 ionic interaction in the trypsin fold. Sci Rep, 9:18035-18035, 2019 Cited by PubMed: 31792294DOI: 10.1038/s41598-019-54564-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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