6PX5
CRYSTAL STRUCTURE OF HUMAN MEIZOTHROMBIN DESF1 MUTANT S195A bound with PPACK
Summary for 6PX5
Entry DOI | 10.2210/pdb6px5/pdb |
Related | 3e6p |
Related PRD ID | PRD_000020 |
Descriptor | Prothrombin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (7 entities in total) |
Functional Keywords | hydrolase, serine protease, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 47745.83 |
Authors | Pelc, L.A.,Koester, S.K.,Chen, Z.,Gistover, N.,Di Cera, E. (deposition date: 2019-07-24, release date: 2019-09-04, Last modification date: 2023-10-11) |
Primary citation | Pelc, L.A.,Koester, S.K.,Chen, Z.,Gistover, N.E.,Di Cera, E. Residues W215, E217 and E192 control the allosteric E*-E equilibrium of thrombin. Sci Rep, 9:12304-12304, 2019 Cited by PubMed: 31444378DOI: 10.1038/s41598-019-48839-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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