6PFO
Crystal structure of N-glycosylated human calcitonin receptor extracellular domain in complex with salmon calcitonin (16-32)
Summary for 6PFO
Entry DOI | 10.2210/pdb6pfo/pdb |
Related PRD ID | PRD_900001 |
Descriptor | Maltodextrin-binding protein,Calcitonin receptor, Calcitonin, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | class b gpcr, glcnac, signaling protein |
Biological source | Escherichia coli More |
Total number of polymer chains | 4 |
Total formula weight | 114056.06 |
Authors | Lee, S.,Pioszak, A.A. (deposition date: 2019-06-21, release date: 2020-02-12, Last modification date: 2020-07-29) |
Primary citation | Lee, S.M.,Jeong, Y.,Simms, J.,Warner, M.L.,Poyner, D.R.,Chung, K.Y.,Pioszak, A.A. Calcitonin Receptor N-Glycosylation Enhances Peptide Hormone Affinity by Controlling Receptor Dynamics. J.Mol.Biol., 432:1996-2014, 2020 Cited by PubMed: 32035902DOI: 10.1016/j.jmb.2020.01.028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
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