6P8B

E.coli LpxD in complex with peptide FITC-RJPXD33

Summary for 6P8B

• Entry DOI: 10.2210/pdb6p8b/pdb
• Descriptor: UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase, FITC-RJPXD33, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: lps synthesis, transferase, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Escherichia coli; More
• Total number of polymer chains: 4
• Total formula weight: 110623.24

Authors

Ma, X.,Shia, S. (deposition date: 2019-06-06, release date: 2019-08-28, Last modification date: 2023-10-11)

• Primary citation: Ma, X.,Prathapam, R.,Wartchow, C.,Chie-Leon, B.,Ho, C.M.,De Vicente, J.,Han, W.,Li, M.,Lu, Y.,Ramurthy, S.,Shia, S.,Steffek, M.,Uehara, T.; Structural and Biological Basis of Small Molecule Inhibition ofEscherichia coliLpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis.; Acs Infect Dis., 6:1480-1489, 2020; PubMed: 31402665; DOI: 10.1021/acsinfecdis.9b00127

Experimental method

X-RAY DIFFRACTION (2 Å)