6P8B

E.coli LpxD in complex with peptide FITC-RJPXD33

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006629	biological_process	lipid metabolic process
A	0009245	biological_process	lipid A biosynthetic process
A	0016020	cellular_component	membrane
A	0016410	molecular_function	N-acyltransferase activity
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
A	0042802	molecular_function	identical protein binding
A	0046677	biological_process	response to antibiotic
A	0103118	molecular_function	UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006629	biological_process	lipid metabolic process
B	0009245	biological_process	lipid A biosynthetic process
B	0016020	cellular_component	membrane
B	0016410	molecular_function	N-acyltransferase activity
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0042802	molecular_function	identical protein binding
B	0046677	biological_process	response to antibiotic
B	0103118	molecular_function	UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006629	biological_process	lipid metabolic process
C	0009245	biological_process	lipid A biosynthetic process
C	0016020	cellular_component	membrane
C	0016410	molecular_function	N-acyltransferase activity
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0042802	molecular_function	identical protein binding
C	0046677	biological_process	response to antibiotic
C	0103118	molecular_function	UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MG A 401

Chain	Residue
A	HOH562
A	HOH677
B	HOH700
B	HOH818
C	HOH622
C	HOH810

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site_id	AC2
Number of Residues	6
Details	binding site for residue MG A 402

Chain	Residue
B	HOH631
C	ASN121
C	HOH684
A	ASN121
A	HOH529
B	ASN121

---

site_id	AC3
Number of Residues	15
Details	binding site for residue O3V B 501

Chain	Residue
A	PHE183
A	TYR185
A	ILE254
A	ALA256
A	ASN274
A	HOH557
B	ILE230
B	ALA250
B	ILE267
B	GLY268
B	GLY269
B	VAL285
B	HOH611
C	GLU49
C	HOH702

---

site_id	AC4
Number of Residues	13
Details	binding site for residue O3V C 501

Chain	Residue
B	GLU49
B	PHE183
B	TYR185
B	ILE254
B	ASN274
B	HOH746
C	ALA250
C	MET266
C	GLY268
C	GLY269
C	HOH604
C	HOH685
C	HOH698

---

Functional Information from PROSITE/UniProt

site_id	PS00101
Number of Residues	29
Details	HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IApsAvIdatAkLGnnVsIGanAvIesgV

Chain	Residue	Details
A	ILE100-VAL128
A	ILE106-VAL134
A	LEU130-VAL158
A	ILE225-VAL253

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	3
Details	Site: {"description":"Involved in determining the hydroxyacyl-ACP selectivity"}

Chain

Residue

Details

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