6OZ4
Crystal structure of broadly neutralizing antibody N49P6 Fab in complex with HIV-1 BG505 SOSIP.664 Env trimer ectodomain.
Summary for 6OZ4
Entry DOI | 10.2210/pdb6oz4/pdb |
Descriptor | Envelope glycoprotein gp160, Envelope glycoprotein gp41, N49P6 antibody Fab heavy chain, ... (9 entities in total) |
Functional Keywords | hiv-1 envelop trimer, gp120, gp41, viral entry, viral protein-immune system complex, type-1 membrane fusion glycoprotein, n49p6, immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 4 |
Total formula weight | 126169.42 |
Authors | Tolbert, W.D.,Pazgier, M. (deposition date: 2019-05-15, release date: 2020-08-19, Last modification date: 2023-10-11) |
Primary citation | Tolbert, W.D.,Nguyen, D.N.,Tehrani, Z.R.,Sajadi, M.M.,Pazgier, M. Near-Pan-neutralizing, Plasma Deconvoluted Antibody N49P6 Mimics Host Receptor CD4 in Its Quaternary Interactions with the HIV-1 Envelope Trimer. Mbio, :e0127421-e0127421, 2021 Cited by PubMed: 34281393DOI: 10.1128/mBio.01274-21 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.05 Å) |
Structure validation
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