6OKD
Crystal Structure of human transferrin receptor in complex with a cystine-dense peptide
Summary for 6OKD
Entry DOI | 10.2210/pdb6okd/pdb |
Descriptor | Transferrin receptor protein 1, transferrin receptor binding cystine-dense peptide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (6 entities in total) |
Functional Keywords | protein-protein complex, cystine-dense peptide, transport protein-signaling protein complex, transport protein/signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 164220.86 |
Authors | Finton, K.A.K.,Rupert, P.B.,Strong, R.K. (deposition date: 2019-04-12, release date: 2020-04-15, Last modification date: 2023-10-11) |
Primary citation | Crook, Z.R.,Girard, E.,Sevilla, G.P.,Merrill, M.,Friend, D.,Rupert, P.B.,Pakiam, F.,Nguyen, E.,Yin, C.,Ruff, R.O.,Hopping, G.,Strand, A.D.,Finton, K.A.K.,Coxon, M.,Mhyre, A.J.,Strong, R.K.,Olson, J.M. A TfR-Binding Cystine-Dense Peptide Promotes Blood-Brain Barrier Penetration of Bioactive Molecules. J.Mol.Biol., 432:3989-4009, 2020 Cited by PubMed: 32304700DOI: 10.1016/j.jmb.2020.04.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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