6OJD
A high-resolution crystal structure of covalent complex of NocB thioesterase domain with fluorophosphonate nocardicin G analog
Summary for 6OJD
Entry DOI | 10.2210/pdb6ojd/pdb |
Related | 6OJC |
Descriptor | NocB, GLYCEROL, (R)-[(S)-[(3S)-3-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoazetidin-1-yl](4-hydroxyphenyl)methyl]methylphosphinic acid, ... (5 entities in total) |
Functional Keywords | nonribosomal peptide synthetase (nrps), thioesterase, epimerization, alpha/beta hydrolase fold, hydrolase |
Biological source | Nocardia uniformis subsp. tsuyamanensis |
Total number of polymer chains | 4 |
Total formula weight | 113918.42 |
Authors | Patel, K.D.,Gulick, A.M. (deposition date: 2019-04-11, release date: 2019-09-11, Last modification date: 2023-10-11) |
Primary citation | Patel, K.D.,d'Andrea, F.B.,Gaudelli, N.M.,Buller, A.R.,Townsend, C.A.,Gulick, A.M. Structure of a bound peptide phosphonate reveals the mechanism of nocardicin bifunctional thioesterase epimerase-hydrolase half-reactions. Nat Commun, 10:3868-3868, 2019 Cited by PubMed: 31455765DOI: 10.1038/s41467-019-11740-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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