6O9O
Crystal Structure of SMYD3 with Potent and Selective Isoxazole Amide Inhibitor 1
Summary for 6O9O
Entry DOI | 10.2210/pdb6o9o/pdb |
Related | 6NTQ |
Descriptor | Histone-lysine N-methyltransferase SMYD3, ZINC ION, MAGNESIUM ION, ... (7 entities in total) |
Functional Keywords | histone, mynd, set, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 50968.66 |
Authors | Elkins, P.A.,Wang, L. (deposition date: 2019-03-14, release date: 2020-03-18, Last modification date: 2024-03-13) |
Primary citation | Su, D.-S.,Elkins, P.A. Discovery of Isoxazole Amides as Potent and Selective SMYD3 Inhibitors To be published, |
Experimental method | X-RAY DIFFRACTION (1.586 Å) |
Structure validation
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