6MCO
Crystal structure of the B41 SOSIP.664 Env trimer with PGT124 and 35O22 Fabs, in P23 space group
Summary for 6MCO
Entry DOI | 10.2210/pdb6mco/pdb |
Descriptor | Transmembrane protein gp41, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (16 entities in total) |
Functional Keywords | viral protein, hiv, envelope, glycoprotein, prefusion trimer, glycan, hiv-1 gp120, hiv-1 gp41, n332 supersite, immune system, neutralizing antibodies, complex, viral protein-immune system complex |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 6 |
Total formula weight | 182196.05 |
Authors | Kumar, S.,Sarkar, A.,Wilson, I.A. (deposition date: 2018-08-31, release date: 2019-02-27, Last modification date: 2023-10-11) |
Primary citation | Kumar, S.,Sarkar, A.,Pugach, P.,Sanders, R.W.,Moore, J.P.,Ward, A.B.,Wilson, I.A. Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide. Nat Commun, 10:763-763, 2019 Cited by PubMed: 30770829DOI: 10.1038/s41467-019-08738-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.526 Å) |
Structure validation
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