6KI0
Crystal Structure of Human ASC-CARD
Summary for 6KI0
Entry DOI | 10.2210/pdb6ki0/pdb |
Related PRD ID | PRD_900009 |
Descriptor | Maltose/maltodextrin-binding periplasmic protein,Apoptosis-associated speck-like protein containing a CARD, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, SULFATE ION, ... (4 entities in total) |
Functional Keywords | death domain fold, immune system |
Biological source | Escherichia coli (strain K12) More |
Total number of polymer chains | 2 |
Total formula weight | 104277.57 |
Authors | |
Primary citation | Xu, Z.,Zhou, Y.,Liu, M.,Ma, H.,Sun, L.,Zahid, A.,Chen, Y.,Zhou, R.,Cao, M.,Wu, D.,Zhao, W.,Li, B.,Jin, T. Homotypic CARD-CARD interaction is critical for the activation of NLRP1 inflammasome. Cell Death Dis, 12:57-57, 2021 Cited by PubMed: 33431827DOI: 10.1038/s41419-020-03342-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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