6JK8
Cryo-EM structure of the full-length human IGF-1R in complex with insulin
Summary for 6JK8
Entry DOI | 10.2210/pdb6jk8/pdb |
EMDB information | 9838 |
Descriptor | Insulin-like growth factor 1 receptor, Insulin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | human type 1 insulin-like growth factor receptor; insulin, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 337682.20 |
Authors | |
Primary citation | Zhang, X.,Yu, D.,Sun, J.,Wu, Y.,Gong, J.,Li, X.,Liu, L.,Liu, S.,Liu, J.,Wu, Y.,Li, D.,Ma, Y.,Han, X.,Zhu, Y.,Wu, Z.,Wang, Y.,Ouyang, Q.,Wang, T. Visualization of Ligand-Bound Ectodomain Assembly in the Full-Length Human IGF-1 Receptor by Cryo-EM Single-Particle Analysis. Structure, 28:555-561.e4, 2020 Cited by PubMed: 32275863DOI: 10.1016/j.str.2020.03.007 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.7 Å) |
Structure validation
Download full validation report