6JBT
Complex structure of toripalimab-Fab and PD-1
Summary for 6JBT
Entry DOI | 10.2210/pdb6jbt/pdb |
Descriptor | Programmed cell death protein 1, Heavy chain, Light chain, ... (6 entities in total) |
Functional Keywords | toripalimab-fab, pd-1, glycosylation, complex structure, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 67055.62 |
Authors | |
Primary citation | Liu, H.,Guo, L.,Zhang, J.,Zhou, Y.,Zhou, J.,Yao, J.,Wu, H.,Yao, S.,Chen, B.,Chai, Y.,Qi, J.,Gao, G.F.,Tan, S.,Feng, H.,Yan, J. Glycosylation-independent binding of monoclonal antibody toripalimab to FG loop of PD-1 for tumor immune checkpoint therapy. Mabs, 11:681-690, 2019 Cited by PubMed: 30892132DOI: 10.1080/19420862.2019.1596513 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.47 Å) |
Structure validation
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