6JBT

Complex structure of toripalimab-Fab and PD-1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	F	Programmed cell death protein 1	polymer	157	17731.8	1	UniProt (Q15116) Pfam (PF07686) In PDB	Homo sapiens (Human)	hPD-1
2	H	Heavy chain	polymer	223	23973.8	1		Mus musculus
3	L	Light chain	polymer	219	23987.8	1		Mus musculus
4	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	2	In PDB GlyTouCan (G21290RB)
5	F	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
6		water	water		18.0	89	Chemie (HOH)

Sequence modifications

F: 2 - 151 (UniProt: Q15116)

PDB	External Database	Details
Met 1	-	initiating methionine
His 152	-	expression tag
His 153	-	expression tag
His 154	-	expression tag
His 155	-	expression tag
His 156	-	expression tag
His 157	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	65693.3
Branched	Number of molecules	2
	Total formula weight	1141.1
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	67055.6

*Water molecules are not included.