6J8E
Human Nav1.2-beta2-KIIIA ternary complex
Summary for 6J8E
Entry DOI | 10.2210/pdb6j8e/pdb |
EMDB information | 9780 |
Descriptor | Sodium channel subunit beta-2, Sodium channel protein type 2 subunit alpha, Mu-conotoxin KIIIA, ... (8 entities in total) |
Functional Keywords | transmembrane protein, membrane protein, membrane protein-toxin complex, membrane protein/toxin |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 251187.00 |
Authors | |
Primary citation | Pan, X.,Li, Z.,Huang, X.,Huang, G.,Gao, S.,Shen, H.,Liu, L.,Lei, J.,Yan, N. Molecular basis for pore blockade of human Na+channel Nav1.2 by the mu-conotoxin KIIIA. Science, 363:1309-1313, 2019 Cited by PubMed: 30765605DOI: 10.1126/science.aaw2999 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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