6HK0
X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) F16'S pore mutant (F247S) with alternate M4 conformation.
Summary for 6HK0
Entry DOI | 10.2210/pdb6hk0/pdb |
Descriptor | Cys-loop ligand-gated ion channel, DODECYL-BETA-D-MALTOSIDE (2 entities in total) |
Functional Keywords | ion channel, pentameric ligand-gated ion channel, cya-loop receptor, membrane protein |
Biological source | Dickeya chrysanthemi (Pectobacterium chrysanthemi) |
Total number of polymer chains | 10 |
Total formula weight | 358668.73 |
Authors | Nury, H.,Spurny, R.,Govaerts, C.,Evans, G.L.,Pardon, E.,Steyaert, J.,Ulens, C. (deposition date: 2018-09-04, release date: 2019-10-09, Last modification date: 2024-01-17) |
Primary citation | Henault, C.M.,Govaerts, C.,Spurny, R.,Brams, M.,Estrada-Mondragon, A.,Lynch, J.,Bertrand, D.,Pardon, E.,Evans, G.L.,Woods, K.,Elberson, B.W.,Cuello, L.G.,Brannigan, G.,Nury, H.,Steyaert, J.,Baenziger, J.E.,Ulens, C. A lipid site shapes the agonist response of a pentameric ligand-gated ion channel. Nat.Chem.Biol., 15:1156-1164, 2019 Cited by PubMed: 31591563DOI: 10.1038/s41589-019-0369-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.45 Å) |
Structure validation
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