6HGA
Crystal Structure of the human IL-17RC D2-D3-D4 domains in complex with an anti-APP tag Fab
Summary for 6HGA
Entry DOI | 10.2210/pdb6hga/pdb |
Related | 6HG4 6HG9 |
Descriptor | Interleukin-17 receptor C, anti-APP-tag Fab heavy-chain, anti-APP-tag Fab light-chain, ... (5 entities in total) |
Functional Keywords | fniii domains, fab complex, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 77996.71 |
Authors | Rondeau, J.M.,Goepfert, A. (deposition date: 2018-08-23, release date: 2020-03-18, Last modification date: 2020-07-29) |
Primary citation | Goepfert, A.,Lehmann, S.,Blank, J.,Kolbinger, F.,Rondeau, J.M. Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling. Immunity, 52:499-512.e5, 2020 Cited by PubMed: 32187518DOI: 10.1016/j.immuni.2020.02.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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