6FS9
Influenza B/Memphis/13/03 endonuclease with I38T mutation with bound inhibitor, baloxavir acid (BXA)
Summary for 6FS9
Entry DOI | 10.2210/pdb6fs9/pdb |
Descriptor | Polymerase acidic protein, MANGANESE (II) ION, Baloxavir acid, ... (5 entities in total) |
Functional Keywords | influenza polymerase, endonuclease, inhibitor, viral protein |
Biological source | Influenza B virus (B/Memphis/13/2003) |
Total number of polymer chains | 1 |
Total formula weight | 24170.87 |
Authors | Cusack, S.,Speranzini, V. (deposition date: 2018-02-19, release date: 2018-07-11, Last modification date: 2024-01-17) |
Primary citation | Omoto, S.,Speranzini, V.,Hashimoto, T.,Noshi, T.,Yamaguchi, H.,Kawai, M.,Kawaguchi, K.,Uehara, T.,Shishido, T.,Naito, A.,Cusack, S. Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep, 8:9633-9633, 2018 Cited by PubMed: 29941893DOI: 10.1038/s41598-018-27890-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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