6FS9
Influenza B/Memphis/13/03 endonuclease with I38T mutation with bound inhibitor, baloxavir acid (BXA)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Polymerase acidic protein | polymer | 205 | 23506.6 | 1 | UniProt (Q5V8Z9) | Influenza B virus (B/Memphis/13/2003) | RNA-directed RNA polymerase subunit P2 |
| 2 | B, C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D (A) | Baloxavir acid | non-polymer | 483.5 | 1 | Chemie (E4Z) | |||
| 4 | E, F (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | G (A) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A: 1 - 197 (UniProt: Q5V8Z9)
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | expression tag |
| Ala -6 | - | expression tag |
| Met -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Met -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Thr 38 | Ile 38 | engineered mutation |
| Ser 60 | Ala 60 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23506.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 664.3 | |
| All* | Total formula weight | 24170.9 |
