6FPU
tRNA guanine Transglycosylase (TGT) in co-crystallized complex with 6-amino-2-((((3aS,5aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methyl)amino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
Summary for 6FPU
Entry DOI | 10.2210/pdb6fpu/pdb |
Related | 5JSV 5JSW |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, GLYCEROL, ... (6 entities in total) |
Functional Keywords | co-crystallization, transferase, transferase inhibitor |
Biological source | Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) |
Total number of polymer chains | 1 |
Total formula weight | 43669.22 |
Authors | Nguyen, A.,Heine, A.,Klebe, G. (deposition date: 2018-02-12, release date: 2019-03-13, Last modification date: 2024-01-17) |
Primary citation | Movsisyan, L.D.,Schafer, E.,Nguyen, A.,Ehrmann, F.R.,Schwab, A.,Rossolini, T.,Zimmerli, D.,Wagner, B.,Daff, H.,Heine, A.,Klebe, G.,Diederich, F. Sugar Acetonides are a Superior Motif for Addressing the Large, Solvent-Exposed Ribose-33 Pocket of tRNA-Guanine Transglycosylase. Chemistry, 24:9957-9967, 2018 Cited by PubMed: 29939431DOI: 10.1002/chem.201801756 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.36 Å) |
Structure validation
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