6F7C

TUBULIN-Compound 12 complex

Summary for 6F7C

Entry DOI	10.2210/pdb6f7c/pdb
Descriptor	Tubulin alpha-1B chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (12 entities in total)
Functional Keywords	cell cycle, tubulin fold, cytoskeleton, microtubule
Biological source	Rattus norvegicus (Rat) More
Total number of polymer chains	6
Total formula weight	264870.68
Authors	Muehlethaler, T.,Prota, A.E.,Steinmetz, M.O. (deposition date: 2017-12-08, release date: 2018-12-19, Last modification date: 2024-01-17)
Primary citation	Cury, N.M.,Muhlethaler, T.,Laranjeira, A.B.A.,Canevarolo, R.R.,Zenatti, P.P.,Lucena-Agell, D.,Barasoain, I.,Song, C.,Sun, D.,Dovat, S.,Yunes, R.A.,Prota, A.E.,Steinmetz, M.O.,Diaz, J.F.,Yunes, J.A. Structural Basis of Colchicine-Site targeting Acylhydrazones active against Multidrug-Resistant Acute Lymphoblastic Leukemia. Iscience, 21:95-109, 2019 Cited by PubMed: 31655259 DOI: 10.1016/j.isci.2019.10.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.002 Å)

Structure validation