6EZF
PDE2 in complex with molecule 5
Summary for 6EZF
Entry DOI | 10.2210/pdb6ezf/pdb |
Descriptor | cGMP-dependent 3',5'-cyclic phosphodiesterase, MAGNESIUM ION, ZINC ION, ... (8 entities in total) |
Functional Keywords | pde2, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 42041.46 |
Authors | Tresadern, G.,Perez-Benito, L.,Keraenen, H.,van Vlijmen, H. (deposition date: 2017-11-15, release date: 2018-04-04, Last modification date: 2024-05-08) |
Primary citation | Perez-Benito, L.,Keranen, H.,van Vlijmen, H.,Tresadern, G. Predicting Binding Free Energies of PDE2 Inhibitors. The Difficulties of Protein Conformation. Sci Rep, 8:4883-4883, 2018 Cited by PubMed: 29559702DOI: 10.1038/s41598-018-23039-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
Download full validation report