6EZF

PDE2 in complex with molecule 5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	cGMP-dependent 3',5'-cyclic phosphodiesterase	polymer	353	41377.3	1	UniProt (O00408) Pfam (PF00233) In PDB	Homo sapiens (Human)	Cyclic GMP-stimulated phosphodiesterase,cGSPDE
2	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
3	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
4	A	6-[(2,4-dichlorophenyl)methyl]pyridazine-3-thiol	non-polymer		271.2	1	Chemie (C6Z)
5	A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
7	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
8		water	water		18.0	347	Chemie (HOH)

Sequence modifications

A: 578 - 919 (UniProt: O00408)

PDB	External Database	Details
Met 575	-	initiating methionine
His 576	-	expression tag
Ala 577	-	expression tag
Leu 920	-	expression tag
Glu 921	-	expression tag
His 922	-	expression tag
His 923	-	expression tag
His 924	-	expression tag
His 925	-	expression tag
His 926	-	expression tag
His 927	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41377.3
Non-Polymers*	Number of molecules	7
	Total formula weight	664.1
All*	Total formula weight	42041.5

*Water molecules are not included.