6EZF
PDE2 in complex with molecule 5
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | cGMP-dependent 3',5'-cyclic phosphodiesterase | polymer | 353 | 41377.3 | 1 | UniProt (O00408) Pfam (PF00233) In PDB | Homo sapiens (Human) | Cyclic GMP-stimulated phosphodiesterase,cGSPDE |
2 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
4 | A | 6-[(2,4-dichlorophenyl)methyl]pyridazine-3-thiol | non-polymer | 271.2 | 1 | Chemie (C6Z) | |||
5 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
6 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
7 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
8 | water | water | 18.0 | 347 | Chemie (HOH) |
Sequence modifications
A: 578 - 919 (UniProt: O00408)
PDB | External Database | Details |
---|---|---|
Met 575 | - | initiating methionine |
His 576 | - | expression tag |
Ala 577 | - | expression tag |
Leu 920 | - | expression tag |
Glu 921 | - | expression tag |
His 922 | - | expression tag |
His 923 | - | expression tag |
His 924 | - | expression tag |
His 925 | - | expression tag |
His 926 | - | expression tag |
His 927 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 41377.3 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 664.1 | |
All* | Total formula weight | 42041.5 |