6EP1

Transthyretin in complex with 5-(4-nitrophenylazo)-3-iodosalicylic acid

Summary for 6EP1

• Entry DOI: 10.2210/pdb6ep1/pdb
• Related: 6EOY
• Descriptor: Transthyretin, 5-(4-nitrophenylazo)-3-iodosalicylic acid (3 entities in total)
• Functional Keywords: amyloid inhibitor, fap inhibitor, transthyretin, transport protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 26038.45

Authors

Leite, J.P.,Gales, L. (deposition date: 2017-10-10, release date: 2018-10-31, Last modification date: 2024-01-17)

• Primary citation: Leite, J.P.,Gales, L.; Targeting transthyretin in Alzheimer's disease: Drug discovery of small-molecule chaperones as disease-modifying drug candidates for Alzheimer's disease; Eur.J.Med.Chem., 2021; DOI: 10.1016/j.ejmech.2021.113847

Experimental method

X-RAY DIFFRACTION (1.3 Å)